DNA repair: a new fan of the Fanconi anaemia pathway

Comment

Katharine H Wrighton. Nat Rev Mol Cell Biol. 2010 Sep.

. 2010 Sep;11(9):603.

doi: 10.1038/nrm2958. Epub 2010 Aug 11.

No abstract available

Comment on

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2.
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Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents.
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A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.
Smogorzewska A, Desetty R, Saito TT, Schlabach M, Lach FP, Sowa ME, Clark AB, Kunkel TA, Harper JW, Colaiácovo MP, Elledge SJ. Smogorzewska A, et al. Mol Cell. 2010 Jul 9;39(1):36-47. doi: 10.1016/j.molcel.2010.06.023. Mol Cell. 2010. PMID: 20603073 Free PMC article.