Different types of resistant starch elicit different glucose reponses in humans

Abstract

The purpose of this study was to determine whether different types of resistant starch (RS) elicited different glycemic responses. Eleven healthy subjects consumed solutions containing 30 g of either dextrose (DEX), resistant starch type 2 (RS2), or cross-linked resistant wheat starch type 4 (RS4(XL)) on three separate occasions, which were assigned randomly. Finger stick blood samples were collected before and over the following two hours and measured for glucose. The incremental area under the curve (iAUC) for the glucose response was calculated for all trials. The two types of resistant starch significantly (P < .05) decreased iAUC compared with DEX. The response with RS4(XL) was significantly decreased compared with the RS2 trial. These data demonstrate that different types of resistant starch elicit significantly different glycemic responses.

Figure 1

The glucose responses to 30 g of carbohydrate from three treatments (DEX, RS2 and RS4_XL). Panel (a) depicts the glucose changes over time, while panel (b) depicts the incremental area under the glucose curve. Data presented are mean±SE; significance was set at P < .05; and, different letters indicate difference between treatments.