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Review
. 2009;2(1):14-29.
doi: 10.1016/j.jiph.2009.02.001. Epub 2009 Mar 5.

The role of infections in the emergence of non-communicable diseases (NCDs): Compelling needs for novel strategies in the developing world

Dimie Ogoina  1 , Geofrey C Onyemelukwe
Affiliations
Review

The role of infections in the emergence of non-communicable diseases (NCDs): Compelling needs for novel strategies in the developing world

Dimie Ogoina et al. J Infect Public Health. 2009.

Abstract

The emergence of non-communicable diseases (NCDs) follows multiple aetiological pathways requiring recognition for effective control and prevention. Infections are proving to be conventional, emerging and re-emerging aetiological factors for many NCDs. This review explores the possible mechanisms by which infections induce NCDs citing examples of studies in Africa and elsewhere where NCDs and infections are proposed or confirmed to be causally linked and also discusses the implications and challenges of these observations for science and medicine. The need to re-evaluate and expand early community and individual preventive and control strategies that will lead to reduction and even elimination of NCDs especially in Africa and other developing countries where infections are prevalent is highlighted.

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Figure 1
Figure 1
Novel integrated approach to NCDs prevention and control in developing countries: identifying and targeting associated infectious risk factors. NB: microbial fingerprints may include microbial DNA, RNA or protein detected by molecular biology techniques.
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