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Case Reports
. 2010 Oct;48(10):3806-9.
doi: 10.1128/JCM.00721-10. Epub 2010 Aug 11.

Neurobrucellosis associated with syndrome of inappropriate antidiuretic hormone with resultant diabetes insipidus and hypothyroidism

Giuseppe Sturniolo  1 , Placido Mondello, Salvatore Bruno, Orsola Elena Bonfatto, Sabrina Frattima, Antonio Albanese, Roberta Restivo, Giuseppe Liberti, Paolo Pasquali, Cinzia Marianelli
Affiliations
Case Reports

Neurobrucellosis associated with syndrome of inappropriate antidiuretic hormone with resultant diabetes insipidus and hypothyroidism

Giuseppe Sturniolo et al. J Clin Microbiol. 2010 Oct.

Abstract

Neurological involvement of the central nervous system in brucellosis is uncommon. We describe a rare case of meningoencephalitis due to Brucella melitensis infection, associated with the syndrome of inappropriate antidiuretic hormone secretion and leading to diabetes insipidus and hypothyroidism. Neurobrucellosis, although rare, should be considered in cases of neurological disease of unknown etiology.

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References

    1. Akdeniz, H., H. Irmak, O. Anlar, and A. P. Demiröz. 1998. Central nervous system brucellosis: presentation, diagnosis and treatment. J. Infect. 36:297-301. - PubMed
    1. al Deeb, S. M., B. A. Yaqub, H. S. Sharif, and J. G. Phadke. 1989. Neurobrucellosis: clinical characteristics, diagnosis, and outcome. Neurology 39:498-501. - PubMed
    1. Al-Sous, M. W., S. Bohlega, M. Z. Al-Kawi, J. Alwatban, and D. R. McLean. 2004. Neurobrucellosis: clinical and neuroimaging correlation. AJNR Am. J. Neuroradiol. 25:395-401. - PMC - PubMed
    1. Alton, G. G., L. M. Jones, R. D. Angus, and J. M. Verger. 1988. Techniques for the Brucellosis Laboratory. Institut National de la Recherche Agronomique Publications, Paris, France.
    1. Aysha, M. H., and M. A. Shayib. 1988. Syndrome of inappropriate secretion of antidiuretic hormone in brucellosis. J. Infect. 17:29-33. - PubMed

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