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Review
. 1991 Jun;14(3):191-8.
doi: 10.1097/00002826-199106000-00001.

Convulsive disorders: status epilepticus

Affiliations
Review

Convulsive disorders: status epilepticus

T P Bleck. Clin Neuropharmacol. 1991 Jun.

Abstract

Status epilepticus (SE) remains one of the most serious disorders affecting the central nervous system. Recent progress in understanding the mechanisms of the brain damage produced by SE make even more apparent the need to quickly terminate this condition, prevent its recurrence, and treat its complications. Intracellular calcium concentrations rise, prompting a cascade of excitotoxic consequences. Therapy for SE currently consists of agents which stop seizures (benzodiazepines, phenytoin, barbiturates). This review discusses their use in SE.

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