SMADs stimulate miRNA processing
- PMID: 20705233
- DOI: 10.1016/j.molcel.2010.07.020
SMADs stimulate miRNA processing
Abstract
MicroRNAs (miRNAs) are potent regulators of gene expression. Consequently, miRNA expression is tightly regulated itself. In this issue, Hata and coworkers provide mechanistic insights into how SMAD proteins regulated the biogenesis of a specific subset of human miRNAs.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha.Mol Cell. 2010 Aug 13;39(3):373-84. doi: 10.1016/j.molcel.2010.07.011. Mol Cell. 2010. PMID: 20705240 Free PMC article.
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