Central odontogenic fibroma: a case report with long-term follow-up

Abstract

An osteolytic tumour of the mandible with prominent expansive growth on the alveolar ridge and displacement of the involved teeth is described in a 28-year-old man. The lesion was diagnosed as a central odontogenic fibroma, an uncommon benign neoplasm derived from dental apparatus, and was removed by curettage. The patient remains asymptomatic after thirteen years of follow-up, which supports the claimed indolent behavior of this poorly documented disease and the adequacy of a conservative surgical treatment.

Figure 1

A - Intra-oral view demonstrating gingival swelling in the alveolar ridge between canine and premolar teeth. B - Periapical radiography demonstrating a radiolucent osteolitic lesion with internal osseous septa, and points of calcifications on buccal surface. Besides, shows a thin radiopaque line around the superior aspect of the lesion and resorption of the lamina dura without radicular resorption.

Figure 2

Microscopic view demonstrating a lesion constituted by fibrous connective tissue and abundant nests and strands of inactive-looking OE usually surrounded by basophilic extra-cellular substance (1000×, hematoxilin-eosin).