Insertion of the Mirena intrauterine system for treatment of adenomyosis-associated menorrhagia: a novel method
- PMID: 20708521
- DOI: 10.1016/S1028-4559(10)60034-4
Insertion of the Mirena intrauterine system for treatment of adenomyosis-associated menorrhagia: a novel method
Abstract
Objective: Insertion of the levonorgestrel-releasing intrauterine system Mirena is difficult in women with adenomyosis, and the device is often subsequently expelled. We used a novel insertion technique (Yang's method) to overcome this problem.
Materials and methods: This retrospective study enrolled 273 patients with adenomyosis who were receiving Mirena for treatment of menorrhagia and/or dysmenorrhea between 2001 and 2008. Clinical outcomes and expulsion rates were compared between patients treated using conventional insertion and those treated using Yang's insertion methods.
Results: Expulsion occurred in 25.3% of patients with the conventional method, compared with 10.2% of patients with Yang's method. Hemoglobin levels and dysmenorrhea improved greatly in both groups after Mirena insertion.
Conclusion: Yang's insertion method for levonorgestrel-releasing intrauterine system is more reliable in some difficult cases, such as patients with severe adenomyosis. This method ensures correct positioning, thus reducing the risks of uterine perforation and/or expulsion.
Copyright 2010 Taiwan Association of Obstetrics and Gynecology. Published by Elsevier B.V. All rights reserved.
Similar articles
-
[Levonorgestrel-releasing intrauterine system for treatment of dysmenorrhea associated with adenomyosis].Zhonghua Fu Chan Ke Za Zhi. 2006 Jul;41(7):467-70. Zhonghua Fu Chan Ke Za Zhi. 2006. PMID: 17083813 Clinical Trial. Chinese.
-
Two for the price of one.Int J STD AIDS. 2008 Oct;19(10):719-20. doi: 10.1258/ijsa.2008.008107. Int J STD AIDS. 2008. PMID: 18824630
-
Levonorgestrel-releasing intrauterine system: uses and controversies.Expert Rev Med Devices. 2008 Jul;5(4):437-45. doi: 10.1586/17434440.5.4.437. Expert Rev Med Devices. 2008. PMID: 18573044 Review.
-
Effectiveness of the levonorgestrel-releasing intrauterine system in the treatment of adenomyosis diagnosed and monitored by magnetic resonance imaging.Contraception. 2007 Sep;76(3):195-9. doi: 10.1016/j.contraception.2007.05.091. Epub 2007 Jul 27. Contraception. 2007. PMID: 17707716
-
Mirena (Levonorgestrel intrauterine system): a successful novel drug delivery option in contraception.Adv Drug Deliv Rev. 2009 Aug 10;61(10):808-12. doi: 10.1016/j.addr.2009.04.022. Epub 2009 May 13. Adv Drug Deliv Rev. 2009. PMID: 19445984 Review.
Cited by
-
The levonorgestrel-releasing intrauterine system in heavy menstrual bleeding: a benefit-risk review.Drugs. 2012 Jan 22;72(2):193-215. doi: 10.2165/11598960-000000000-00000. Drugs. 2012. PMID: 22268392 Review.
-
Risk factors and countermeasures for abnormal uterine bleeding during dienogest therapy for adenomyosis: a review.Front Reprod Health. 2025 Jun 30;7:1550814. doi: 10.3389/frph.2025.1550814. eCollection 2025. Front Reprod Health. 2025. PMID: 40662092 Free PMC article. Review.
-
Efficacy of hysteroscopic levonorgestrel‑releasing intrauterine device fixation in the treatment of adenomyosis: A cohort study.Biomed Rep. 2024 Jun 4;21(1):109. doi: 10.3892/br.2024.1797. eCollection 2024 Jul. Biomed Rep. 2024. PMID: 38868528 Free PMC article.
-
The suture fixation of the levonorgestrel-releasing intrauterine device with hysteroscope for the treatment of adenomyosis in patients at high risk of device expulsion-a prospective observational study.BMC Womens Health. 2024 Oct 9;24(1):556. doi: 10.1186/s12905-024-03390-8. BMC Womens Health. 2024. PMID: 39385236 Free PMC article.
-
Utility of the Levonorgestrel-Releasing Intrauterine System in the Treatment of Abnormal Uterine Bleeding and Dysmenorrhea: A Narrative Review.J Clin Med. 2022 Oct 1;11(19):5836. doi: 10.3390/jcm11195836. J Clin Med. 2022. PMID: 36233703 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical