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Comment
. 2010 Aug 17;19(2):185-6.
doi: 10.1016/j.devcel.2010.07.023.

Getting one's Fak straight

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Comment

Getting one's Fak straight

Gerard Evan. Dev Cell. .

Abstract

Focal adhesion kinase (FAK) is a pivotal regulator of integrin signaling and responses to cell adhesive dynamics. In this issue of Developmental Cell, Ashton et al. demonstrate that Fak is critical for intestinal oncogenesis and regeneration after injury but not for day-to-day homeostasis, providing novel insights into intestinal biology and colorectal cancer therapy.

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References

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