Autophagy employs a new DAGger against bacteria
- PMID: 20709289
- DOI: 10.1016/j.chom.2010.07.009
Autophagy employs a new DAGger against bacteria
Abstract
Autophagy can orchestrate innate immune responses to bacterial infection by targeting invading pathogens for lysosomal degradation. In this issue of Cell Host & Microbe, Shahnazari et al. (2010) unveil the role played by the diacylglycerol-PKC pathway in the routing of intracellular Salmonella to autophagy.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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A diacylglycerol-dependent signaling pathway contributes to regulation of antibacterial autophagy.Cell Host Microbe. 2010 Aug 19;8(2):137-46. doi: 10.1016/j.chom.2010.07.002. Epub 2010 Jul 30. Cell Host Microbe. 2010. PMID: 20674539 Free PMC article.
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