Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2010;14(4):184.
doi: 10.1186/cc9083. Epub 2010 Aug 6.

The interpretation of brain natriuretic peptide in critical care patients; will it ever be useful?

John Dixon  1 , Barbara Philips
Affiliations
Comment

The interpretation of brain natriuretic peptide in critical care patients; will it ever be useful?

John Dixon et al. Crit Care. 2010.

Abstract

The measurement of B-type natriuretic peptide (BNP) is recommended for the diagnosis of decompensated heart failure, the prognosis of chronic heart failure is worse if BNP is increased and studies suggest that BNP is useful to guide therapy. A study by Di Somma and colleagues adds to the body of evidence showing that patients with a marked decrease in BNP concentrations during their hospital admission are less likely to be readmitted with a further adverse cardiac event than patients in whom BNP fails to decrease. However, the wider interpretation of BNP concentrations in critically ill patients with other conditions remains uncertain.

PubMed Disclaimer

Comment on

Similar articles

See all similar articles

Cited by

References

    1. Di Somma S, Magrini L, Pittoni V, Marino R, Mastrantuono A, Ferri E, Ballarino P, Semplicini A, Bertazzoni G, Carpinteri G, Mule P, Pazzaglia M, Shah K, Maisel A, Clopton P. In-hospital percentage BNP reduction is highly predictive for adverse events in patients admitted for acute heart failure: the Italian RED Study. Crit Care. 2010;14:R116. doi: 10.1186/cc9067. - DOI - PMC - PubMed
    1. Cheng V, Kazanagra R, Garcia A, Lenert L, Krishnaswamy P, Gardetto N, Clopton P, Maisel A. A rapid bedside test for B-type peptide predicts treatment outcomes in patients admitted for decompensated heart failure: a pilot study. J Am Coll Cardiol. 2001;37:386–391. doi: 10.1016/S0735-1097(00)01157-8. - DOI - PubMed
    1. Wang TJ, Larson MG, Levy D, Benjamin EJ, Leip EP, Omland T, Wolf PA, Vasan RS. Plasma natriuretic peptide levels and the risk of cardiovascular events and death. N Engl J Med. 2004;350:655–663. doi: 10.1056/NEJMoa031994. - DOI - PubMed
    1. Anand IS, Fisher LD, Chiang YT, Latini R, Masson S, Maggioni AP, Glazer RD, Tognoni G, Cohn JN. Val-HeFT Investigators. Changes in brain natriuretic peptide and norepinephrine over time and mortality and morbidity in the Valsartan Heart Failure Trial (Val-HeFT) Circulation. 2003;107:1278–1283. doi: 10.1161/01.CIR.0000054164.99881.00. - DOI - PubMed
    1. Doust JA, Pietrzak E, Dobson A, Glasziou P. How well does B-type natriuretic peptide predict death and cardiac events in patients with heart failure: systematic review. BMJ. 2005;330:625. doi: 10.1136/bmj.330.7492.625. - DOI - PMC - PubMed

LinkOut - more resources