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. 2010 Sep-Oct;19(5):416-21.
doi: 10.1111/j.1521-0391.2010.00064.x.

Co-occurring psychiatric symptoms are associated with increased psychological, social, and medical impairment in opioid dependent pregnant women

Margaret M Benningfield  1 , Amelia M Arria, Karol Kaltenbach, Sarah H Heil, Susan M Stine, Mara G Coyle, Gabriele Fischer, Hendrée E Jones, Peter R Martin
Affiliations

Co-occurring psychiatric symptoms are associated with increased psychological, social, and medical impairment in opioid dependent pregnant women

Margaret M Benningfield et al. Am J Addict. 2010 Sep-Oct.

Abstract

The interaction of psychiatric symptoms with drug dependence during pregnancy is not well understood. This study examines the relationship of psychiatric symptoms to severity of drug use and drug-related problems among participants in a clinical trial of pharmacologic treatment of opioid dependence during pregnancy (N = 174). A total of 64.6% reported additional psychiatric symptoms (48.6% mood symptoms, 40.0% anxiety symptoms, and 12.6% suicidal thinking). Women who endorsed co-occurring psychiatric symptoms showed more severe impairment on the Addiction Severity Index. Further investigation is warranted to understand the effect of psychiatric symptoms on long-term maternal and neonatal outcomes.

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