Review
doi: 10.2967/jnumed.109.065656.
Epub 2010 Aug 18.
Molecular imaging of the dopamine transporter
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- PMID: 20720060
- DOI: 10.2967/jnumed.109.065656
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Review
Molecular imaging of the dopamine transporter
J Nucl Med.
2010 Sep.
Free article
Abstract
The dopamine transporter (DAT) is a transmembrane protein responsible for reuptake of dopamine from the synaptic cleft and termination of dopaminergic transmission. Several radioligands are available for DAT imaging with SPECT and PET. This review summarizes the main SPECT and PET radioligands and the main applications of DAT imaging in neuropsychiatric disorders.
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