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Review
. 2010;49(16):1801-5.
doi: 10.2169/internalmedicine.49.3164. Epub 2010 Aug 13.

CD3- and CD4-positive plasmablastic lymphoma: a literature review of Japanese plasmablastic lymphoma cases

Yuhko Suzuki  1 , Tsutomu Yoshida, Naoya Nakamura, Hirotoshi Kamata, Shouko Kotani, Manabu Ohsaka, Sabine Kajita, Koji Miyazaki, Shinichi Ohtani, Meijin Nakayama, Ryouichi Horie, Kazushige Hayakawa, Nozomi Niitsu, Masaaki Higashihara
Affiliations
Free article
Review

CD3- and CD4-positive plasmablastic lymphoma: a literature review of Japanese plasmablastic lymphoma cases

Yuhko Suzuki et al. Intern Med. 2010.
Free article

Abstract

Plasmablastic lymphoma (PBL) is a very rare and recently-described subtype of diffuse large B-cell lymphoma. A maxillary tumor in an 84-year-old HIV-negative Japanese-man was referred. The biopsied specimen showed a diffuse proliferation of mature plasma cells, expressing CD3 (+), CD4 (+), CD20 (-), CD138 (+) and EBER (+) by immunohistochemistry. He was diagnosed as a plasmablastic lymphoma; radiation therapy (RT) was started, but the response to the RT was only a partial response. To our knowledge, this is the first report of a patient with PBL expressing CD3 and CD4.

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