doi: 10.1128/JVI.65.8.4547-4549.1991.
Transcellular transactivation by the human immunodeficiency virus type 1 tat protein
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- PMID: 2072464
- PMCID: PMC248903
- DOI: 10.1128/JVI.65.8.4547-4549.1991
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Transcellular transactivation by the human immunodeficiency virus type 1 tat protein
J Virol.
1991 Aug.
Abstract
The human immunodeficiency virus type 1 (HIV-1) transactivator (tat) protein produced in one cell activated HIV-1 promoter-directed gene expression in a second cell, provided the cells were in direct contact with one another. This observation suggests that the tat protein produced in HIV-1-infected cells has a physiological effect on neighboring cells.
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