Antiretroviral therapy as HIV prevention: status and prospects
- PMID: 20724682
- PMCID: PMC2936983
- DOI: 10.2105/AJPH.2009.184796
Antiretroviral therapy as HIV prevention: status and prospects
Abstract
As antiretroviral treatment of HIV infection has become increasingly accessible, attention has focused on whether these drugs can used for prevention because of increased tolerability of newer medications, decreased cost, and the limitations of other approaches. We review the status of antiretroviral HIV prevention, including chemoprophylaxis, as well as the effects of treatment of infected individuals on prevention. It is possible that the life-saving agents that have transformed the natural history of AIDS can be a critical component of HIV prevention efforts, but their ultimate role in affecting HIV transmission dynamics remains to be defined.
Figures


Comment in
-
Preserving human rights in the era of "test and treat" for HIV prevention.Am J Public Health. 2011 Feb;101(2):198-9; author reply 199-200. doi: 10.2105/AJPH.2010.300050. Am J Public Health. 2011. PMID: 21228278 Free PMC article. No abstract available.
References
-
- UNAIDS 2008 update on the global AIDS epidemic. Available at: http://www.unaids.org/en/KnowledgeCentre/HIVData/GlobalReport/2008j. Accessed June 1, 2009
-
- Markel H. The search for effective HIV vaccines. N Engl J Med. 2005;353(8):753–757 - PubMed
-
- Johnston MI, Fauci AS. An HIV vaccine—evolving concepts. N Engl J Med. 2007;356(20):2073–2081 - PubMed
-
- Klasse PJ, Shattock R, Moore JP. Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission. Annu Rev Med. 2008;59:455–471 - PubMed
-
- Mocroft A, Ledergerber B, Katlama C, et al. Decline in the AIDS and death rates in the EuroSIDA study: an observational study. Lancet. 2003;362(9377):22–29 - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical
Research Materials