Management of high-risk cutaneous squamous cell carcinoma
- PMID: 20725546
- PMCID: PMC2921745
Management of high-risk cutaneous squamous cell carcinoma
Abstract
Cutaneous squamous cell carcinoma is an increasing public health concern, representing the second most common cancer in the United States. High-risk cutaneous squamous cell carcinoma represents a subgroup of this disease, where patients are at higher risk of metastasis and death. To date, there are no accepted criteria for defining or managing these patients. This review discusses the current state of knowledge of high-risk cutaneous squamous cell carcinoma and outlines reasonable management strategies based on available data.
References
-
- Miller DL, Weinstock MA. Nonmelanoma skin cancer in the United States: incidence. J Am Acad Dermatol. 1994;30(5 Pt 1):774–778. - PubMed
-
- Rowe DE, Carroll RJ, Day CL., Jr Prognostic factors for local recurrence, metastasis, and survival rates in squamous cell carcinoma of the skin, ear, and lip. Implications for treatment modality selection. J Am Acad Dermatol. 1992;26(6):976–990. - PubMed
-
- Brantsch KD, Meisner C, Schonfisch B, et al. Analysis of risk factors determining prognosis of cutaneous squamous cell carcinoma: a prospective study. Lancet Oncol. 2008;9(8):713–720. - PubMed
-
- Jambusaria-Pahlajani A KK, Hess, SD, Berg D, Schmults CD. Uncertainty in the peri-operative management of high-risk cutaneous squamous cell carcinoma among Mohs surgeons. Arch Dermatol. In press. - PubMed
-
- Cherpelis BS, Marcusen C, Lang PG. Prognostic factors for metastasis in squamous cell carcinoma of the skin. Dermatol Surg. 2002;28(3):268–273. - PubMed
LinkOut - more resources
Full Text Sources