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. 2010 Dec;23(6):845-8.
doi: 10.1111/j.1755-148X.2010.00753.x. Epub 2010 Aug 18.

Quantitative measurement of circulating lymphoid-specific helicase (HELLS) gene transcript: a potential serum biomarker for melanoma metastasis

Hye-Eun Kim, James T Symanowski, Erika E Samlowski, Jason Gonzales, Byungwoo Ryu

Quantitative measurement of circulating lymphoid-specific helicase (HELLS) gene transcript: a potential serum biomarker for melanoma metastasis

Hye-Eun Kim et al. Pigment Cell Melanoma Res. 2010 Dec.
No abstract available

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Figures

Figure 1
Figure 1
Distribution patterns of circulating gene transcripts in patient sera and area under the receiver operating characteristic (AUC-ROC) curves. (A) Comparison of quantitative mRNA copy number for the genes HELLS, NCAPH, TYMS, BIRC5, and ACTB in patient sera among the sample groups (N: normal control, P: patients with Stage 0/1 primary melanomas, M: patients with Stage IV metastatic melanomas). ACTB served as a negative control. (B) Comparison of serum LDH concentrations in the patients with primary and metastatic melanomas. (C) AUC-ROC curves for each individual analyte are shown. Analyte HELLS shows the highest value.
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