Alpha-2 adrenoceptor agonists and sepsis: improved survival?
- PMID: 20727233
- PMCID: PMC2945092
- DOI: 10.1186/cc9096
Alpha-2 adrenoceptor agonists and sepsis: improved survival?
Comment on
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Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.Crit Care. 2010;14(2):R38. doi: 10.1186/cc8916. Epub 2010 Mar 16. Crit Care. 2010. PMID: 20233428 Free PMC article. Clinical Trial.
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References
-
- Pandharipande PP, Sanders RD, Girard TD, McGrane S, Thompson JL, Shintani AK, Herr DL, Maze M, Ely EW, Mends IT. Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial. Crit Care. 2010;14:R38. doi: 10.1186/cc8916. - DOI - PMC - PubMed
-
- Pichot C, Mathern P, Khettab F, Ghignone M, Geloen A, Quintin L. Increased pressor response to noradrenaline during septic shock following clonidine? Anesthesia Intensive Care (Sydney) 2010. in press . - PubMed
-
- Venn RM, Newman PJ, Grounds RM. A phase II study to evaluate the efficacy of dexmedetomidine for sedation in the medical intensive care unit. Int Care Med. 2003;29:201–207. - PubMed
-
- Spies CD, Dubisz N, Neumann T, Blum S, Muller C, Rommelspacher H, Brummer G, Specht M, Sanft C, Hannemann L, Striebel HW, Schaff artzik W. Therapy of alcohol withdrawal syndrome in intensive care unit patients following trauma: results of a prospective, randomized trial. Crit Care Med. 1996;24:414–422. doi: 10.1097/00003246-199603000-00009. - DOI - PubMed
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