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. 2010 Sep;68(1):89-92.
doi: 10.1016/j.diagmicrobio.2010.04.012.

Evolving microbiology of complicated acute otitis media before and after introduction of the pneumococcal conjugate vaccine in France

Damien Dupont  1 , Farah Mahjoub-Messai, Martine François, Catherine Doit, Patricia Mariani-Kurkdjian, Philippe Bidet, Stéphane Bonacorsi, Agnès Carol, Edouard Bingen
Affiliations

Evolving microbiology of complicated acute otitis media before and after introduction of the pneumococcal conjugate vaccine in France

Damien Dupont et al. Diagn Microbiol Infect Dis. 2010 Sep.

Abstract

We compare the microbiology of otopathogens causing recurrent acute otitis media (AOM) or AOM treatment failure in 600 children during 2000 to 2008 before and after the introduction of 7-valent pneumococcal conjugate vaccine (PCV-7). Streptococcus pneumoniae predominated before PCV-7 introduction and during 2007 to 2008, whereas Haemophilus influenzae predominated during 2005 to 2006. S. pneumoniae 19A became the most frequent serotype after PCV-7 introduction.

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