Ubiquilin at a crossroads in protein degradation pathways
- PMID: 20729634
- PMCID: PMC3359474
- DOI: 10.4161/auto.6.7.13118
Ubiquilin at a crossroads in protein degradation pathways
Abstract
Ubiquilin proteins are conserved across all eukaryotes and function in the regulation of protein degradation. We found that ubiquilin functions to regulate macroautophagy and that the protein is also a substrate of chaperone-mediated autophagy.
References
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- Hum Mol Genet. 2010 Aug 15;19(16):3219-32 - PubMed
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