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. 2009 Jun;2(6):36-8.

Solitary sclerotic fibroma

Avani Bhambri  1 , James Q Del Rosso
Affiliations

Solitary sclerotic fibroma

Avani Bhambri et al. J Clin Aesthet Dermatol. 2009 Jun.

Abstract

Sclerotic fibroma is a rare skin neoplasm that can be seen sporadically or in association with disorders such as Cowden's disease. We present a case of solitary sclerotic fibroma that presented as an asymptomatic nodule in a 40-year-old man with no evidence of Cowden's disease. Histopathologically, the lesion was consistent with a sclerotic fibroma displaying hypocellular collagen bundles with clefts.

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Figures

Figure 1
Figure 1
A 1.5cm, soft, flesh-colored, waxy plaque on the right temporal scalp
Figure 2
Figure 2
A low-power view showing the classic plywood-like pattern with prominent clefts
Figure 3
Figure 3
A high-power view revealing prominent clefts among hyalinized collagen. Scattered fibroblast nuclei present
Figure 4
Figure 4
Histiocytes showing positive staining with CD68
See this image and copyright information in PMC

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