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. 2010 Dec;10(8):1286-8.
doi: 10.1016/j.meegid.2010.08.010. Epub 2010 Aug 21.

Avian-origin H3N2 canine influenza A viruses in Southern China

Shoujun Li  1 , Zhihai Shi, Peirong Jiao, Guihong Zhang, Zhiwen Zhong, Wenru Tian, Li-Ping Long, Zhipeng Cai, Xingquan Zhu, Ming Liao, Xiu-Feng Wan
Affiliations

Avian-origin H3N2 canine influenza A viruses in Southern China

Shoujun Li et al. Infect Genet Evol. 2010 Dec.

Abstract

This study reports four sporadic cases of H3N2 canine influenza in Southern China, which were identified from sick dogs from May 2006 to October 2007. The evolutionary analysis showed that all eight segments of these four viruses are avian-origin and phylogenetically close to the H3N2 canine influenza viruses reported earlier in South Korea. Systematic surveillance is required to monitor the disease and evolutionary behavior of this virus in canine populations in China.

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Figures

Figure 1
Figure 1. Phylogenetic analysis and molecular characterization of H3N2 canine influenza viruses isolated from southern China
(A) The phylogenetic tree for HA gene; (B) The phylogenetic tree for NA gene. The phylogenetic trees were constructed using maximum likelihood implemented in GARLI version 0.96, and the bootstrap values were generated using neighborhood joining methods implemented in PAUP* with 1,000 replications.
Figure 1
Figure 1. Phylogenetic analysis and molecular characterization of H3N2 canine influenza viruses isolated from southern China
(A) The phylogenetic tree for HA gene; (B) The phylogenetic tree for NA gene. The phylogenetic trees were constructed using maximum likelihood implemented in GARLI version 0.96, and the bootstrap values were generated using neighborhood joining methods implemented in PAUP* with 1,000 replications.
Figure 2
Figure 2. The mutations in HA protein surface area of H3N2 avian-origin canine influenza viruses
The template of H3 three-dimensional structure used here is 1HGD, which is downloaded from the Protein Data Bank (www.pdb.org).
See this image and copyright information in PMC

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