Interferon regulatory factor 4: combinational control of lymphocyte differentiation
- PMID: 20732634
- DOI: 10.1016/j.immuni.2010.08.007
Interferon regulatory factor 4: combinational control of lymphocyte differentiation
Abstract
Transcriptional mechanisms involved in the differentiation of the recently identified interleukin-9 (IL-9) secreting T helper cell subset are still poorly defined. In this issue of Immunity, Staudt et al. (2010) now report an essential role for the interferon regulatory factor-4 in IL-9 production.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells.Immunity. 2010 Aug 27;33(2):192-202. doi: 10.1016/j.immuni.2010.07.014. Epub 2010 Jul 30. Immunity. 2010. PMID: 20674401
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