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. 2010 Sep 17;12(18):4110-3.
doi: 10.1021/ol101702w.

Copper-catalyzed olefin aminoacetoxylation

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Copper-catalyzed olefin aminoacetoxylation

Danny E Mancheno et al. Org Lett. .

Abstract

A new catalyst system for intramolecular olefin aminoacetoxylation is described. In contrast to previously reported palladium- and copper-catalyzed systems, the conditions outlined in this communication favor piperdine formation with terminal olefin substrates and induce cyclization with traditionally less reactive disubstituted olefins.

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