Infection
- PMID: 20736799
- PMCID: PMC4408554
- DOI: 10.1097/BOT.0b013e3181eebf12
Infection
Abstract
Musculoskeletal infection is a clinical problem with significant direct healthcare costs. The prevalence of infection after closed, elective surgery is frequently estimated to be less than 2%, but in severe injuries, posttraumatic infection rates have been reported as 10% or greater. Although clinical infections are found outside the realm of medical devices, it is clear that the enormous increase of infections associated with the use of implants presents a major challenge worldwide. This review summarizes recent advances in the understanding, diagnosis, and treatment of musculoskeletal infections.
References
-
- Costerson JW, Lenandowski Z, Caldwell DE, et al. Microbial biofilms. Annu Rev Microbiol. 1995;49:711–745. - PubMed
-
- Beveridge TJ, Makin SA, Kadurugamuwa JL, et al. Interactions between biofilms and the environment. FEMS Microbiol Rev. 1997;20:291–303. - PubMed
-
- Webb LX, Wagner W, Carroll D, et al. Osteomyelitis and intraosteoblastic S aureus. J Surg Orthop Adv. 2007;16:73–77. - PubMed
-
- Pillai RR, Somayaji SN, Rabinovich M, et al. Nafcillin-loaded PLGA nanoparticles for treatment of osteomyelitis. Biomed Mater. 2008;3:034114. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical