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Review
. 2010:678:147-56.
doi: 10.1007/978-1-4419-6306-2_19.

Chemo brain (chemo fog) as a potential side effect of doxorubicin administration: role of cytokine-induced, oxidative/nitrosative stress in cognitive dysfunction

Christopher D Aluise  1 , Rukhsana Sultana, Jitbangjong Tangpong, Mary Vore, Daret St Clair, Jeffrey A Moscow, D Allan Butterfield
Affiliations
Review

Chemo brain (chemo fog) as a potential side effect of doxorubicin administration: role of cytokine-induced, oxidative/nitrosative stress in cognitive dysfunction

Christopher D Aluise et al. Adv Exp Med Biol. 2010.

Abstract

Doxorubicin (ADRIAMYCIN, RUBEX) is a chemotherapeutic agent that is commonly administered to breast cancer patients in standard chemotherapy regimens. As true of all such therapeutic cytotoxic agents, it can damage normal, noncancerous cells and might affect biochemical processes in a manner that might lead to, or contribute to, chemotherapy-induced cognitive deficits when administered either alone or in combination with other agents.

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