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Case Reports
. 2009 Apr 25;2(1):72-76.
doi: 10.1159/000214838.

PSA Decrease with Fulvestrant Acetate in a Hormone-Resistant Metastatic Prostate Cancer Patient: A Case Report

Joan Manel Gasent Blesa  1 , Vicente Alberola Candel
Affiliations
Case Reports

PSA Decrease with Fulvestrant Acetate in a Hormone-Resistant Metastatic Prostate Cancer Patient: A Case Report

Joan Manel Gasent Blesa et al. Case Rep Oncol. .

Abstract

Metastatic prostate cancer is an incurable disease. After a period of hormone sensitivity that allows for the use of antiandrogens, the disease invariably progresses to a situation of androgen-independent growth, which deserves the consideration or the use of chemotherapy. As many of these patients are elderly and fragile, treatment with chemotherapy is challenging. Therefore, new drugs are required. Preclinical evidence supports the role of estrogen receptor (ER) signaling in prostate cancer. In this paper, we report the first published evidence of PSA control in a patient with metastatic prostate cancer treated with fulvestrant acetate.

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Figures

Fig. 1
Fig. 1
PSA level dynamics.
See this image and copyright information in PMC

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