Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1990 Dec 14;12(6A):262-6; discussion 267.
doi: 10.1007/BF01967830.

Pharmacokinetics and tissue concentrations of cefuroxime

T B Vree  1 , Y A Hekster
Affiliations
Review

Pharmacokinetics and tissue concentrations of cefuroxime

T B Vree et al. Pharm Weekbl Sci. .

Abstract

Cefuroxime is well-absorbed and distributed over the human body. This review gives a general summary of published information on tissue concentrations of cefuroxime after an intravenous or intramuscular dose of 750 or 1,500 mg of cefuroxime. Tissue concentrations are given for blister fluid, meninges, eyes, respiratory tract, sputum and bronchi, abdominal and urogenital tract, uterine, ovarian and fallopian tube tissue, myometrium, membranes, placenta, puruloid and healthy human milk, bile, prostate, hip and knee bone. Pharmacokinetics are reviewed in patients with impaired kidney function and in pregnancy.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Proc R Soc Med. 1977;70(Suppl 9):38-41 - PubMed
    1. Chemotherapy. 1988;34(1):1-7 - PubMed
    1. Antimicrob Agents Chemother. 1989 Jul;33(7):1108-10 - PubMed
    1. J Antimicrob Chemother. 1982 Apr;9(4):303-11 - PubMed
    1. Am J Obstet Gynecol. 1982 Apr 1;142(7):823-8 - PubMed