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Review
. 2010 May;48(5):425-35.

Free radicals: their beneficial and detrimental effects on sperm function

Shiva Kothari  1 , Aaron Thompson, Ashok Agarwal, Stefan S du Plessis
Affiliations
  • PMID: 20795359
Review

Free radicals: their beneficial and detrimental effects on sperm function

Shiva Kothari et al. Indian J Exp Biol. 2010 May.

Abstract

Free radicals are molecules with one or more unpaired electron(s) commonly found in seminal plasma. Physiologically, free radicals control sperm maturation, capacitation and hyperactivation, the acrosome reaction, and sperm-oocyte fusion. Pathologically, free radicals induce lipid peroxidation, DNA damage and apoptosis of spermatozoa. The present review deals with both the beneficial and detrimental effects of free radicals on sperm function.

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