Alterations in the surface properties of cells responsive to nerve growth factor
- PMID: 208002
- DOI: 10.1038/273718a0
Alterations in the surface properties of cells responsive to nerve growth factor
Abstract
An initial effect of nerve growth factor on a responsive nerve cell line is to increase intracellular cyclic AMP, which in turn leads to a mobilisation of calcium ions. These events are correlated with structural changes in the plasma membrane, increased cell-substratum adhesion, and neurite outgrowth.
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