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. 1978 Jun 29;273(5665):718-23.
doi: 10.1038/273718a0.

Alterations in the surface properties of cells responsive to nerve growth factor

D Schubert, M LaCorbiere, C Whitlock, W Stallcup

Alterations in the surface properties of cells responsive to nerve growth factor

D Schubert et al. Nature. .

Abstract

An initial effect of nerve growth factor on a responsive nerve cell line is to increase intracellular cyclic AMP, which in turn leads to a mobilisation of calcium ions. These events are correlated with structural changes in the plasma membrane, increased cell-substratum adhesion, and neurite outgrowth.

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