N-of-1 clinical trials should be incorporated into clinical practice
- PMID: 20800449
- DOI: 10.1016/j.jclinepi.2010.05.006
N-of-1 clinical trials should be incorporated into clinical practice
Abstract
N-of-1 clinical trials have the potential to contribute to individual patient management and to the accrual of important information about populations. Incorporating these studies into clinical practice will require creative thinking so as to maintain rigor without excessive disruption of routine care.
Copyright © 2010 Elsevier Inc. All rights reserved.
Comment on
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Individual (N-of-1) trials can be combined to give population comparative treatment effect estimates: methodologic considerations.J Clin Epidemiol. 2010 Dec;63(12):1312-23. doi: 10.1016/j.jclinepi.2010.04.020. Epub 2010 Sep 22. J Clin Epidemiol. 2010. PMID: 20863658 Free PMC article.
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