Effects of resveratrol and flavonols on cardiovascular function: Physiological mechanisms
- PMID: 20803524
- DOI: 10.1002/biof.111
Effects of resveratrol and flavonols on cardiovascular function: Physiological mechanisms
Abstract
Resveratrol and flavonols are commonly found together in fruits and vegetables and, therefore, consumed in the diet. These two polyphenols share both vasorelaxant and antioxidant activity and may act together to improve cardiovascular function. This review examines the mechanisms by which resveratrol and flavonols influence cardiovascular function and perhaps offer a new approach for the development of therapeutic agents for the prevention and/or treatment of coronary artery disease.
© 2010 International Union of Biochemistry and Molecular Biology, Inc.
Similar articles
-
Flavonols and cardiovascular disease.Mol Aspects Med. 2010 Dec;31(6):478-94. doi: 10.1016/j.mam.2010.09.002. Epub 2010 Sep 15. Mol Aspects Med. 2010. PMID: 20837053 Review.
-
Understanding the cardioprotective effects of flavonols: discovery of relaxant flavonols without antioxidant activity.J Med Chem. 2008 Mar 27;51(6):1874-84. doi: 10.1021/jm070352h. Epub 2008 Feb 29. J Med Chem. 2008. PMID: 18307286
-
Discovery of water-soluble antioxidant flavonols without vasorelaxant activity.ChemMedChem. 2008 Oct;3(10):1572-9. doi: 10.1002/cmdc.200800146. ChemMedChem. 2008. PMID: 18756557
-
Effects of dietary polyphenols on gene expression in human vascular endothelial cells.Proc Nutr Soc. 2008 Feb;67(1):42-7. doi: 10.1017/S0029665108006009. Proc Nutr Soc. 2008. PMID: 18234130 Review.
-
[The polyphenols, naturally occurring compounds with beneficial effects on cardiovascular disease].Nutr Hosp. 2012 Jan-Feb;27(1):76-89. doi: 10.1590/S0212-16112012000100009. Nutr Hosp. 2012. PMID: 22566306 Review. Spanish.
Cited by
-
3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries.PLoS One. 2011;6(6):e20813. doi: 10.1371/journal.pone.0020813. Epub 2011 Jun 6. PLoS One. 2011. PMID: 21673968 Free PMC article.
-
Brain "fog," inflammation and obesity: key aspects of neuropsychiatric disorders improved by luteolin.Front Neurosci. 2015 Jul 3;9:225. doi: 10.3389/fnins.2015.00225. eCollection 2015. Front Neurosci. 2015. PMID: 26190965 Free PMC article. Review.
-
Flavonols in the Prevention of Diabetes-induced Vascular Dysfunction.J Cardiovasc Pharmacol. 2015 Jun;65(6):532-44. doi: 10.1097/FJC.0000000000000180. J Cardiovasc Pharmacol. 2015. PMID: 25387248 Free PMC article. Review.
-
Dietary patterns and changes in cardiovascular risk factors in apparently healthy Chinese women: a longitudinal study.J Clin Biochem Nutr. 2016 May;58(3):232-9. doi: 10.3164/jcbn.15-78. Epub 2016 Apr 13. J Clin Biochem Nutr. 2016. PMID: 27257349 Free PMC article.
-
3',4'-Dihydroxyflavonol Modulates the Cell Cycle in Cancer Cells: Implication as a Potential Combination Drug in Osteosarcoma.Pharmaceuticals (Basel). 2021 Jul 3;14(7):640. doi: 10.3390/ph14070640. Pharmaceuticals (Basel). 2021. PMID: 34358066 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical