Comment on

• The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

  Simsek T, Kocabas F, Zheng J, Deberardinis RJ, Mahmoud AI, Olson EN, Schneider JW, Zhang CC, Sadek HA. Simsek T, et al. Cell Stem Cell. 2010 Sep 3;7(3):380-90. doi: 10.1016/j.stem.2010.07.011. Cell Stem Cell. 2010. PMID: 20804973 Free PMC article.
• Regulation of the HIF-1alpha level is essential for hematopoietic stem cells.

  Takubo K, Goda N, Yamada W, Iriuchishima H, Ikeda E, Kubota Y, Shima H, Johnson RS, Hirao A, Suematsu M, Suda T. Takubo K, et al. Cell Stem Cell. 2010 Sep 3;7(3):391-402. doi: 10.1016/j.stem.2010.06.020. Cell Stem Cell. 2010. PMID: 20804974