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. 2010 Jul;7(7):9-12.

Real-world Data on Atypical Antipsychotic Medication Side Effects

Elisa Cascade  1 , Amir H Kalali, Sagar Mehra, Jonathan M Meyer
Affiliations

Real-world Data on Atypical Antipsychotic Medication Side Effects

Elisa Cascade et al. Psychiatry (Edgmont). 2010 Jul.

Abstract

In this article, we provide information on patient-reported side effects from a cross-section of real-world patients. Specifically, data on side effects were tabulated for patients taking at least one of the following atypical antipsychotic medications: aripiprazole, olanzapine, paliperidone, quetiapine, risperidone, or ziprasidone. Approximately 54 percent of the 353 respondents reported having experienced a side effect as a result of taking an atypical antipsychotic medication. Most common side effects mentioned included the following: weight gain/hunger, tiredness/lethargy, and lack of coordination/muscle problems, such as tenderness, twitches, and tremors. Of those experiencing a side effect, less than 25 percent reported this side effect to their physician.

Keywords: Aripiprazole; atypical antipsychotic; olanzapine; paliperidone; quetiapine; risperidone; schizophrenia; self report; side effect; ziprasidone.

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Figures

Figure 1
Figure 1
Most commonly mentioned side effects (n=172 patients listing at least 1 side effect) All other mentions are <5% prevalence. SOURCE: Analysis of www.iGuard.org data for aripiprazole, olanzapine, paliperidone, quetiapine, risperidone, or ziprasidone
Figure 2
Figure 2
Impact of side effects SOURCE: Analysis of www.iGuard.org data for aripiprazole, olanzapine, paliperidone, quetiapine, risperidone, or ziprasidone
Figure 3
Figure 3
Patients reporting side effects to their physician SOURCE: Analysis of www.iGuard.org data for aripiprazole, olanzapine, paliperidone, quetiapine, risperidone, or ziprasidone
Figure 4
Figure 4
Obesity is associated with medication nonadherence in schizophrenia (N=239) SOURCE: Weiden P et al. Schiz Res. 2004:66;51–57.
See this image and copyright information in PMC

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