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Comparative Study
. 1990 Dec;29(4):219-28.
doi: 10.1007/BF02023079.

[Comparison of the biological activity and stability of menadione and menadiol in male chickens]

[Article in German]
J Gropp  1 , W Mehringer
Affiliations
Comparative Study

[Comparison of the biological activity and stability of menadione and menadiol in male chickens]

[Article in German]
J Gropp et al. Z Ernahrungswiss. 1990 Dec.

Abstract

A bioassay of vitamin K is described, based on the prothrombin clotting time of 3-week-old, vitamin-K-depleted, and cumatetralyl-sensitized male broiler chicks, using a homologous thrombokinase preparation. With this test it could be shown that the diacetate and dibutyrate esters of menadiol are vitamin-K-active. The bioactivity of menadione from these menadiolesters amounted to about 70% of the standard menadione from a coated menadione sodium bisulfite (Dohyfral). Menadiol seems to be temperature-resistant under such conditions, whereby two uncoated MSB preparations lost about 60% of their activity.

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References

    1. Biochem J. 1978 Jan 1;169(1):95-101 - PubMed
    1. Z Tierphysiol Tierernahr Futtermittelkd. 1975 Apr;34(6):325-41 - PubMed
    1. Nutr Rev. 1982 Oct;40(10):311-3 - PubMed
    1. Int J Vitam Nutr Res. 1983;53(2):143-55 - PubMed
    1. Physiol Rev. 1977 Jan;57(1):1-70 - PubMed

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