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. 1990;31(3):287-95.
doi: 10.1186/BF03547541.

Ovine white-liver disease (OWLD). Serum copper and effects of copper and selenium supplementation

M J Ulvund  1
Affiliations

Ovine white-liver disease (OWLD). Serum copper and effects of copper and selenium supplementation

M J Ulvund. Acta Vet Scand. 1990.

Abstract
in English, Swedish

Serum copper was generally higher in lambs affected with ovine white-liver disease (OWLD) than in cobalt/vitamin B12 supplemented lambs grazing the same pastures. Although the copper content of the grass was very low on the OWLD pastures, dosing lambs with Cu alone resulted in worsening of the clinical condition and aggravation of clinical pathology. Dosing with selenium had no effect on OWLD. Dosing with a combination of Co, Se and Cu resulted in normal lamb growth and normal laboratory tests. Lambs growing well on other pastures (H) showed elevated serum Cu when they were subclinically B12 deficient.

Serum kopper var som regel høyere hos lam med kvitleversjuke (OWLD) enn hos dem som fikk tilskudd av kobolt eller vitamin Β12. Til tross for att graset på sjukdomsbeitene var kopperfattig ble sjukdomstilstanden forverret når lam på disse beitene ble dosert med kopper, og forandringene i blodbildet ble forsterket. Dosering med selen hadde ingen virkning på sjukdommen. Dosering med en kombinasjon av kobolt, selen og kopper resulterte i normal tilvekst, og normale forhold i blodbildet. Kontrollama viste stigning i serum kopper når de var subklinisk Co/B12 deficitte.

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