Successful treatment of a prosthetic joint infection due to Mycobacterium abscessus
- PMID: 20808461
- PMCID: PMC2770307
- DOI: 10.1155/2009/968052
Successful treatment of a prosthetic joint infection due to Mycobacterium abscessus
Abstract
Prosthetic joint infection due to Mycobacterium abscessus is uncommon and optimal therapy remains poorly defined. Following a two-stage revision, clinical and microbiological cure was achieved in a patient with a M abscessus-infected total hip arthroplasty. A prolonged course of directed antibacterial therapy comprising clarithromycin and cefoxitin coupled with the application of amikacin-impregnated cement likely contributed to the successful outcome.
L’infection d’une prothèse articulaire causée par le Mycobacterium abscessus est rare, et le traitement optimal demeure mal défini. Après un examen en deux étapes, on a pu obtenir la guérison clinique et microbiologique d’un patient dont l’arthroplastie totale de la hanche était infectée par le M abscessus. Un thérapie antibactérienne dirigée prolongée composée de clarithromycine et de céfoxitine, couplée à l’application d’un ciment imprégné d’amikacine, a probablement contribué à l’issue positive.
Keywords: Mycobacterium abscessus; Prosthetic joint infection; Total hip arthroplasty.
References
-
- Petrini B. Mycobacterium abscessus: an emerging rapid-growing potential pathogen. APMIS. 2006;114:319–28. - PubMed
-
- Mueller PS, Edson RS. Disseminated Mycobacterium abscessus infection manifesting as fever of unknown origin and intra-abdominal lymphadenitis: Case report and literature review. Diagn Microbiol Infect Dis. 2001;39:33–7. - PubMed
-
- Springer B, Bottger EC, Kirschner P, et al. Phylogeny of the Mycobacterium chelonae-like organism based on partial sequencing of the 16S rRNA gene and proposal of Mycobacterium mucogenicum sp. nov. Int J Syst Bacteriol. 1995;45:262–7. - PubMed
-
- Eid AJ, Berbari EF, Sia IG, et al. Prosthetic joint infection due to rapidly growing mycobacteria: Report of 8 cases and review of the literature. Clin Infect Dis. 2007;45:687–94. - PubMed
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