Prognostic indicators of poor outcome in horses with laminitis at a tertiary care hospital
- PMID: 20808574
- PMCID: PMC2871359
Prognostic indicators of poor outcome in horses with laminitis at a tertiary care hospital
Abstract
This retrospective study investigated the factors associated with a poor outcome (death by euthanasia or from other causes) in horses treated for laminitis at a tertiary care hospital. Cases (n = 247) were defined as patients with laminitis that were euthanized or that died of other causes during hospitalization. Controls (n = 344) were patients with laminitis that survived to be discharged from the hospital. In the final multivariate analysis, the factors significantly associated with an increased risk for death and their respective odds ratios (OR) were as follows: Thoroughbred (OR = 1.57); racehorse (OR = 1.76); treatment with flunixin meglumine (OR = 1.76); vascular pathology (OR = 2.12); distal displacement of the third phalanx (OR = 2.68); pneumonia (OR = 2.87); and lameness of Obel grade II (OR = 2.99), grade III (OR = 9.63), or grade IV (OR = 20.48). The use of glue-on shoes significantly reduced the risk for death (OR = 0.36).
Indicateurs d’un pronostic de mauvais résultats chez les chevaux atteints de laminite dans une clinique de soins tertiaires. Cette étude rétrospective a examiné les facteurs associés à de mauvais résultats (mort par euthanasie ou pour d’autres causes) chez les chevaux traités pour la laminite dans une clinique de soins tertiaires. Les cas (n = 247) étaient définis comme des patients atteints de la laminite qui ont été euthanasiés ou qui sont morts d’autres causes durant l’hospitalisation. Les témoins (n = 344) étaient des patients atteints de laminite qui avaient survécu au congé de la clinique. Dans l’analyse finale multicritères, les facteurs présentant une association significative avec le risque accru de mort et leurs ratios respectifs d’incidence (RI) étaient les suivants : Thoroughbred (RI = 1,57); cheval de course (RI = 1,76); traitement à la flunixin méglumine (RI = 1,76); pathologie vasculaire (RI = 2,12); déplacement distal de la troisième phalange (RI = 2,68); pneumonie (RI = 2,87); et boiterie de grade Obel II (RI = 2,99), de grade III (RI = 9,63) ou de grade IV (RI = 20,48). L’usage de fers collés réduisait significativement le risque de mort (RI = 0,36).
(Traduit par Isabelle Vallières)
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References
-
- Stick JA, Jann HW, Scott EA, et al. Pedal bone rotation as a prognostic sign in laminitis of horses. J Am Vet Med Assoc. 1982;180:251–253. - PubMed
-
- Baxter GM. Equine laminitis caused by distal displacement of the distal phalanx: 12 cases (1976–1985) J Am Vet Med Assoc. 1986;189:326–329. - PubMed
-
- Hunt RJ. A retrospective evaluation of laminitis in horses. Equine Vet J. 1993;25:61–64. - PubMed
-
- Cripps PJ, Eustace RA. Factors involved in the prognosis of equine laminitis in the UK. Equine Vet J. 1999;31:433–442. - PubMed
-
- Obel N. Studies on the histopathology of acute laminitis. Almquist and Wiskells; Uppsala, Sweden: 1948.
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