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. 2009 Jul;2(2):127-39.
doi: 10.4103/0974-2069.58314.

Role of myocardial perfusion single photon emission computed tomography in pediatric cardiology practice

P Shanmuga Sundaram  1 , S Padma
Affiliations

Role of myocardial perfusion single photon emission computed tomography in pediatric cardiology practice

P Shanmuga Sundaram et al. Ann Pediatr Cardiol. 2009 Jul.

Abstract

Diagnostic and prognostic power of myocardial perfusion imaging in patients with coronary artery disease has been demonstrated with planar imaging which was further improvised with addition of gated SPECT and newer Technetium labeled myocardial perfusion tracers like SestaMIBI, Tetrofosmin. Myocardial perfusion abnormalities at rest and after stress are considered to be the best predictors of cardiac event-free survival in adults with ischemic heart disease. This article highlights various myocardial perfusion imaging (MPI) radiopharmaceuticals, exercise procedures, pharmacological stress protocols, indications for MPI and myocardial perfusion patterns in children with some of the common congenital and acquired heart diseases.

Keywords: Kawasaki disease; pediatric myocardial perfusion; scintigraphy.

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Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
Post-stress planar image showing more than normal hepatic uptake of SestaMIBI in a 2-month-old male with congenital heart disease and thyroid agenesis
Figure 2a
Figure 2a
99mTc MIBI normal stress myocardial perfusion single photon emission computed tomography
Figure 2b
Figure 2b
Mammary gland attenuation artifact in an adolescent patient - fixed perfusion defect in anterior segment
Figure 3
Figure 3
Stress MPI images of a 6-year-old male with a large lateral wall LV aneurysm. Stress SPECT images show moderate reversible perfusion defects in apex and inferior segments
Figure 4
Figure 4
Left ventricular angiogram images of a 6-year-old male with a large lateral wall LV aneurysm.
Figure 5a
Figure 5a
Same day stress - rest MIBI SPECT images (displayed in two different color scales) of a 12-year-old patient with Kawasaki disease showing mild reversible ischemia in the apex, anteroapical, and septal segments of the LV
Figure 5b
Figure 5b
Same day stress - rest MIBI SPECT images (displayed in two different color scales) of a 12-year-old patient with Kawasaki disease showing mild reversible ischemia in the apex, anteroapical, and septal segments of the LV
Figure 6
Figure 6
Rest SPECT images of an uncorrected tetrology of Fallot patient with biventricular dysfunction. Images show right ventricular enlargement, hypertrophy, and associated septal hypertrophy. There are no perfusion defects in LV myocardial segments at rest
Figure 7
Figure 7
Stress and rest single photon emission computed tomography images of an asymptomatic adolescent boy with uncorrected ALCAPA syndrome showing left anterior descending artery territory ischemia in the background of an old infarct
Figure 8
Figure 8
Rest gated MIBI SPECT images in a patient with dilated cardiomyopathy. Apparent perfusion defects seen in the apex and inferior segments of the LV myocardium
See this image and copyright information in PMC

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