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Case Reports
. 2010 Sep;6(3):286-90.
doi: 10.3171/2010.5.PEDS09289.

Low-grade myofibroblastic sarcoma of the sacrum

Affiliations
Case Reports

Low-grade myofibroblastic sarcoma of the sacrum

William E Humphries 3rd et al. J Neurosurg Pediatr. 2010 Sep.

Abstract

Myofibroblastic tumors are soft-tissue neoplasms arising from myofibroblasts, ubiquitous cells sharing ultrastructural features of muscular and fibroblastic cells. Vasudev and Harris described a malignant counterpart of these benign tumors in 1978. Most reported cases of myofibroblastic sarcoma have arisen in the head and neck region and the soft tissues of the extremities. To the best of the authors' knowledge, there have been only 8 previous reports on primary myofibroblastic sarcoma of the bone. The authors report a new case of this rare tumor affecting the sacrum and ilium of a 15-year-old girl and discuss the role of total sacrectomy and lumbopelvic reconstruction for treatment of this disease.

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