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Review
. 2010 Sep;83(3):664-71.
doi: 10.4269/ajtmh.2010.09-0755.

Dengue Fever in mainland China

Jin-Ya Wu  1 , Zhao-Rong Lun, Anthony A James, Xiao-Guang Chen
Affiliations
Review

Dengue Fever in mainland China

Jin-Ya Wu et al. Am J Trop Med Hyg. 2010 Sep.

Abstract

Dengue is an acute emerging infectious disease transmitted by Aedes mosquitoes and has become a serious global public health problem. In mainland China, a number of large dengue outbreaks with serious consequences have been reported as early as 1978. In the three decades from 1978 to 2008, a total of 655,324 cases were reported, resulting in 610 deaths. Since the 1990s, dengue epidemics have spread gradually from Guangdong, Hainan, and Guangxi provinces in the southern coastal regions to the relatively northern and western regions including Fujian, Zhejiang, and Yunnan provinces. As the major transmission vectors of dengue viruses, the biological behavior and vectorial capacity of Aedes mosquitoes have undergone significant changes in the last two decades in mainland China, most likely the result of urbanization and global climate changes. In this review, we summarize the geographic and temporal distributions, the serotype and genotype distributions of dengue viruses in mainland China, and analyze the current status of surveillance and control of vectors for dengue transmission.

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Figures

Figure 1.
Figure 1.
Annual number of dengue fever cases in mainland China from 1978 to 2008. Data for 1978–2002 are summarized in Refs. 7–10. Data for 2003–2008 are derived from reports of the State Ministry of Public Heath (http://www.moh.gov.cn/publicfiles/business/htmlfiles/zwgkzt/pyq/index.htm).
Figure 2.
Figure 2.
Annual number of dengue fever cases in Guangdong Province from 1990 to 2008. The 1990–2000 and 2001–2006 data are from Refs. 8 and 9. The 2007–2008 data are from reports of the State Ministry of Public Health (http://www.moh.gov.cn/publicfiles/business/htmlfiles/zwgkzt/pyq/index.htm).
Figure 3.
Figure 3.
Approximate distribution of dengue and Aedes mosquitoes in mainland China. ZJ: Zhejiang Province; FJ: Fujian Province; GD: Guangdong Province; GX: Guangxi Province; HN: Hainan Province, YN: Yunnan Province. Data are summarized in Refs. 7, 8, 10–13.
Figure 4.
Figure 4.
Total number of dengue fever cases reported monthly from 2002 to 2008. Data are summarized from (http://www.moh.gov.cn/publicfiles/business/htmlfiles/zwgkzt/pyq/index.htm).
Figure 5.
Figure 5.
The epidemics of four serotypes of dengue virus in mainland China. ZJ: Zhejiang Province; FJ: Fujian Province; GD: Guangdong Province; GX: Guangxi Province; HN: Hainan Province, YN: Yunnan Province. Data are summarized in Refs. , , –. There were 56 cases of DF in Yunnan Province (2008) according to the report from the Department of Health [http://www.moh.gov.cn/publicfiles/business/htmlfiles/zwgkzt/pyq/index.htm], but no publication regarding the serotype of this virus caused this outbreak was found. This figure appears in color at www.ajtmh.org.
See this image and copyright information in PMC

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