Molecular profiling: moving away from tumor philately
- PMID: 20811040
- DOI: 10.1126/scitranslmed.3001329
Molecular profiling: moving away from tumor philately
Abstract
Despite the remarkable enhancements in breast cancer classification and characterization, an exhaustive comprehension of the underlying carcinogenic processes and an accurate prediction of its clinical behavior are yet to be achieved. On the wave of recent scientific advances and clinical findings, new cutting-edge technologies are poised to deliver an array of diverse molecular data that are expected to dramatically alter breast cancer diagnosis and treatment.
Similar articles
-
Mixture classification model based on clinical markers for breast cancer prognosis.Artif Intell Med. 2010 Feb-Mar;48(2-3):129-37. doi: 10.1016/j.artmed.2009.07.008. Epub 2009 Dec 14. Artif Intell Med. 2010. PMID: 20005686
-
Application of molecular findings to the diagnosis and management of breast disease: recent advances and challenges.Hum Pathol. 2011 Feb;42(2):153-65. doi: 10.1016/j.humpath.2010.07.008. Epub 2010 Nov 24. Hum Pathol. 2011. PMID: 21106225
-
Microarray-based gene expression profiling as a clinical tool for breast cancer management: are we there yet?Int J Surg Pathol. 2009 Aug;17(4):285-302. doi: 10.1177/1066896908328577. Epub 2008 Dec 22. Int J Surg Pathol. 2009. PMID: 19103611 Review.
-
Multiple biomarkers in molecular oncology. II. Molecular diagnostics applications in breast cancer management.Expert Rev Mol Diagn. 2007 May;7(3):269-80. doi: 10.1586/14737159.7.3.269. Expert Rev Mol Diagn. 2007. PMID: 17489734 Review.
-
[Breast cancer and molecular markers].Gan To Kagaku Ryoho. 2008 Aug;35(8):1261-8. Gan To Kagaku Ryoho. 2008. PMID: 18701834 Review. Japanese.
Cited by
-
Identification of novel biomarkers associated with poor patient outcomes in invasive breast carcinoma.Tumour Biol. 2016 Oct;37(10):13855-13870. doi: 10.1007/s13277-016-5133-8. Epub 2016 Aug 2. Tumour Biol. 2016. PMID: 27485113
-
Genomic instability at the 13q31 locus and somatic mtDNA mutation in the D-loop site correlate with tumor aggressiveness in sporadic Brazilian breast cancer cases.Clinics (Sao Paulo). 2012 Oct;67(10):1181-90. doi: 10.6061/clinics/2012(10)10. Clinics (Sao Paulo). 2012. PMID: 23070345 Free PMC article.
-
Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction.Breast Cancer Res. 2011 Jun 27;13(3):212. doi: 10.1186/bcr2890. Breast Cancer Res. 2011. PMID: 21787441 Free PMC article. Review.
-
Molecular Subtypes and Local-Regional Control of Breast Cancer.Surg Oncol Clin N Am. 2018 Jan;27(1):95-120. doi: 10.1016/j.soc.2017.08.005. Surg Oncol Clin N Am. 2018. PMID: 29132568 Free PMC article. Review.
-
Breast cancer - one term, many entities?J Clin Invest. 2011 Oct;121(10):3789-96. doi: 10.1172/JCI57100. Epub 2011 Oct 3. J Clin Invest. 2011. PMID: 21965335 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical