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Comment
. 2010 Sep 3;142(5):672-4.
doi: 10.1016/j.cell.2010.08.022.

Fishing out a sensor for anti-inflammatory oils

Alan R Saltiel  1
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Free article
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Fishing out a sensor for anti-inflammatory oils

Alan R Saltiel. Cell. .
Free article

Abstract

The omega-3 fatty acids have anti-inflammatory and antidiabetic effects in humans. Now, Oh et al. (2010) demonstrate that the G protein-coupled receptor GPR120 is a receptor for omega-3 fatty acids on macrophages and fat cells. Activation of GPR120 by omega-3 fatty acids inhibits multiple inflammation cascades in macrophages and reverses insulin resistance in obese mice.

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