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Comment
. 2010 Sep 3;142(5):676-8.
doi: 10.1016/j.cell.2010.08.021.

Viable rat-mouse chimeras: where do we go from here?

Davor Solter  1
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Viable rat-mouse chimeras: where do we go from here?

Davor Solter. Cell. .
Free article

Abstract

In a tour-de-force study, Kobayashi et al. (2010) describe the first viable rat-mouse chimeras and demonstrate that rat induced pluripotent stem (iPS) cells can rescue organ deficiency in mice. Rat iPS cells formed a fully functional pancreas when injected into mouse blastocysts lacking the Pdx1 gene required for pancreas formation.

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