Braak staging in mouse models of Alzheimer's disease
- PMID: 20813967
- PMCID: PMC2947256
- DOI: 10.2353/ajpath.2010.100656
Braak staging in mouse models of Alzheimer's disease
Abstract
In the present paper by David E. Hurtado and colleagues report on a new mouse model for AD bearing Aβ and MAPT pathology by crossing PS19 and PDAPP Tg mice. Here, we tried to highlight the importance and necessity of the critical and systematic analysis of models such as the Braak like staging in AD mouse models.
Comment on
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A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model.Am J Pathol. 2010 Oct;177(4):1977-88. doi: 10.2353/ajpath.2010.100346. Epub 2010 Aug 27. Am J Pathol. 2010. PMID: 20802182 Free PMC article.
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