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. 2011 Jan;95(1):455-7.
doi: 10.1016/j.fertnstert.2010.07.1092.

A mutant single nucleotide polymorphism of follicle-stimulating hormone receptor is associated with a lower risk of endometriosis

Hsin-Shih Wang  1 , Bi-Hwa Cheng, Hsien-Ming Wu, Chih-Feng Yen, Chun-Ting Liu, Angel Chao, Tzu-Hao Wang
Affiliations
Free article

A mutant single nucleotide polymorphism of follicle-stimulating hormone receptor is associated with a lower risk of endometriosis

Hsin-Shih Wang et al. Fertil Steril. 2011 Jan.
Free article

Abstract

Six hundred thirty-seven Taiwanese Chinese women including 300 patients with endometriosis and 337 controls without endometriosis were enrolled to investigate the association between nonsynonymous single nucleotide polymorphism of the FSH receptor gene and the risk of endometriosis. For the A/G polymorphism of FSH receptor gene (Asn680Ser), a univariate analysis for women with endometriosis demonstrated that both the GG genotype (680Ser/Ser) and GA genotype (680Ser/Asn) were associated with a significantly lower risk of endometriosis.

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