[Treatment of toxoplasmosis. The treatment of toxoplasmic chorioretinitis]

Abstract

Toxoplasmosis is the commonest cause of inflammatory disease of the posterior segment of the eye. We treated 23 patients with acute toxoplasma chorioretinitis with sulfonamides, pyrimethamine and corticosteroids for a period of 4 weeks. All patients with acute disease had characteristic foci and a positive titer on the Sabin-Feldman dye test. In all patients, we observed clinical improvement within 2 weeks, but one patient with a lesion larger than 2 disc diameters improved after the third week. During the follow-up period ranging from 6 months to 6 years (mean 2.5 years), there have been four recurrences (17%). No serious side effects of treatment were observed in our patients.