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. 2008;3(s2):1-2.
doi: 10.1159/000151735. Epub 2008 Oct 15.

The Role of uPA and uPA Inhibitors in Breast Cancer

Paul Bevan  1 , Carola Mala
Affiliations

The Role of uPA and uPA Inhibitors in Breast Cancer

Paul Bevan et al. Breast Care (Basel). 2008.
No abstract available

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Figures

Fig. 1
Fig. 1
The urokinase plasminogen activator system: components and biological functions. uPA, Urokinase-type plasminogen activator; uPAR, urokinase-type plasminogen activator receptor; PAI, plasminogen activator inhibitor; Bcl-2, B cell lymphoma 2; ECM, extracellular matrix; ERK, extracellular signal-regulated kinase; FAK, focal adhesion kinase; FGF-2, fibroblast growth factor 2; MAPK, mitogen-activated protein kinase; MMPs, matrix metalloproteinases; mTOR, mammalian target of rapamycin; PI3K, phosphatidylinositol 3-kinase; TGF-β, transforming growth factor beta; VEGF, vascular endothelial growth factor; Vn, vitronectin.
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